Aging + Wrinkles

Understand your skin

The more you know about your skin’s aging process, the better you’ll be able to keep it looking its best. Scroll down for helpful information and tips about between the brow frown lines and wrinkles so you and your healthcare provider can decide if Dysport is right for you.

Frown line facts

Fact 1: Creams & lotions aren’t your only options.

When it comes to improving the look of moderate to severe frown lines between the eyebrows, a prescription treatment may be the right choice for lasting results.

Fact 2: It’s not just an age thing.

Wrinkles and frown lines between the brows are caused by repeated movements and muscle contractions¹, which means they can even develop in younger adults.

Dysport helps you soften frown lines between your brows—with natural-looking, long-lasting results.

Fact 3: You can fight frown lines.

Life happens – and so do wrinkles. Dysport is here to help you soften lines between your eyebrows, so you can live the look that’s expressly you.

Aging education

Let’s get serious about skin.

Yes, there’s a science behind youthful-looking skin. It starts with hyaluronic acid, the naturally occurring substance in your skin that helps give it a full, youthful look.² As we age, hyaluronic acid diminishes, causing our skin to look thinner, drier and more wrinkled.^2,3 Several other scientific factors may lead to less youthful skin with more wrinkles, including:

Redistribution of facial fat³
- Loss of fat in the forehead and cheeks
- Gain of fat in the mouth and jaw area, which can cause sagging
Bone loss throughout your face⁴
Muscle laxity⁴
External factors, such as sun damage or smoking⁴

Aging tips

Avoid UV exposure.

Excessive exposure to ultraviolet rays is thought to be a major culprit for rapidly aging skin. Sun damages your skin and causes a loss of collagen, which can lead to drooping and wrinkles.² If you’re the outdoorsy type, think sunblock and shade to help keep your skin as healthy and young-looking as possible.

Stay hydrated.

Drinking plenty of water will help prevent your skin from becoming overly dry.

Avoid processed foods and sugars.

When sugar comes in contact with collagen (a protein), a reaction called glycation occurs. Glycation can damage collagen, compromise the integrity and regeneration of skin tissue, and accelerate aging of the skin.^5,6

Aging in men

Gentlemen, congratulations on making the bold choice to treat your frown lines between your eyebrows. The fact is, because your face moves when you frown, smile or squint, frown lines can still appear even if you use the best men’s skin care products. And, as a man, your expression lines tend to be deeper, so a prescription injection could be the treatment you need to get the natural look you want. Check out our gallery to see how Dysport can help improve the appearance of between-the-brow frown lines for men.

Aging in women

Work out. Eat right. Take care of your skin. Rinse. Repeat. It’s your every day. Everything you do in your daily routine can help you stay happy and healthy. But sometimes, for those inevitable things in life — like frown lines between the eyebrows — a step outside the routine may be in order. Everybody ages differently, but if you express yourself through movements in your face (like most people do), Dysport can help smooth those frown lines and get the natural look you want. See how Dysport works.

See below for Dysport Important Safety Information and Medication Guide.

References

Molina B, Grangier Y, Mole B, et al. Ribe N. Patient satisfaction after the treatment of glabellar lines with Botulinum toxin type A (Speywood Unit): a multi-centre, prospective, non-interventional European observational study. J Eur Acad Dermatol Venereol. 2015;29(7):1382-1388.
Papakonstantinou E, Roth M, Karakiulakis G. Hyaluronic Acid: A key molecule in skin aging. Dermatoendocrinol. 2012;4(3):253-258.
Vleggaar D, Fitzgerald R. Dermatological implications of skeletal aging: a focus on supraperiosteal volumization for perioral rejuvenation. J Drugs Dermatol. 2008;7(3):209-220.
Ganjoo A. 35A Aging Skin. In: Venkataram M, ed. ACS(I) Textbook on Cutaneous & Aesthetic Surgery. New Delhi: Jaypee Brothers Medical Publishers; 2012:545-549.
Lyons TJ, Bailie KE, Dyer DG, Dunn JA, Baynes JW. Decrease in skin collagen glycation with improved glycemic control in patients with insulin-dependent diabetes mellitus. J Clin Invest. 1991;87(6):1910-1915.
Dandby FW. Nutrition and aging skin: sugar and glycation. Clin Dermatol. 2010;28(4):409-411.

Ask your specialist if prescription Dysport is right for you.

Dysport may not be right for you if: you have surgical changes to your face, very weak muscles in the treatment area, your face looks very different from side to side, the injection site is inflamed, you have droopy eyelids or sagging eyelid folds, deep facial scars, thick oily skin, or if your wrinkles can’t be smoothed by spreading them apart.

See below for Dysport Important Safety Information and Medication Guide.

IMPORTANT SAFETY INFORMATION

Dysport® (abobotulinumtoxinA) is a prescription injection for temporary improvement in the look of moderate to severe frown lines between the eyebrows (glabellar lines) in adults less than 65 years of age.

Important Safety Information

What is the most important information you should know about Dysport? Spread of Toxin Effects: In some cases, the effects of Dysport and all botulinum toxin products may affect areas of the body away from the injection site. Symptoms can happen hours to weeks after injection and may include swallowing and breathing problems, loss of strength and muscle weakness all over the body, double vision, blurred vision and drooping eyelids, hoarseness or change or loss of voice, trouble saying words clearly, or loss of bladder control. Swallowing and breathing problems can be life threatening and there have been reports of death. You are at the highest risk if these problems are pre‐existing before injection.

These effects could make it unsafe for you to drive a car, operate machinery, or do other dangerous activities.

Do not have Dysport treatment if you: are allergic to Dysport or any of its ingredients (see the end of the Medication Guide for a list of ingredients), are allergic to cow’s milk protein, had an allergic reaction to any other botulinum toxin product, such as Myobloc®, Botox®, or Xeomin®, have a skin infection at the planned injection site, under 18 years of age, or are pregnant or breastfeeding.

The dose of Dysport is not the same as the dose of any other botulinum toxin product and cannot be compared to the dose of any other product you may have used.

Tell your doctor about any swallowing or breathing difficulties and all your muscle or nerve conditions such as amyotrophic lateral sclerosis [ALS or Lou Gehrig’s disease], myasthenia gravis, or Lambert‐Eaton syndrome, which may increase the risk of serious side effects including difficulty swallowing and difficulty breathing. Serious allergic reactions have occurred with the use of Dysport. Dry eye has also been reported.

Tell your doctor about all of your medical conditions, including if you have surgical changes to your face, very weak muscles in the treatment area, any abnormal facial change, injection site inflammation, droopy eyelids or sagging eyelid folds, deep facial scars, thick oily skin, wrinkles that can’t be smoothed by spreading them apart, or if you are pregnant or breastfeeding or planning to become pregnant or breastfeed.

Tell your doctor about all the medicines you take, including prescription and nonprescription medicines, vitamins and herbal and other natural products. Using Dysport with certain other medicines may cause serious side effects. Do not start any new medicines while taking Dysport without talking to your doctor first.

Especially tell your doctor if you: have received any other botulinum toxin product, such as Myobloc® (rimabotulinumtoxinB), Botox® (onabotulinumtoxinA), or Xeomin® (incobotulinumtoxinA), in the last four months or any in the past (be sure your doctor knows exactly which product you received), have recently received an antibiotic by injection, take muscle relaxants, take an allergy or cold medicine, or take a sleep medicine.

Common Side Effects

The most common side effects are nose and throat irritation, headache, injection site pain, injection site skin reaction, upper respiratory tract infection, eyelid swelling, eyelid drooping, sinus inflammation, and nausea.

Ask your doctor if Dysport is right for you.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.