as seen in

How to Take Control

of the Aging Process
Sponsored by Dysport® (abobotulinumtoxinA) for Injection | June 15, 2016.
You know the drill: Wash face, apply cream, wear sunscreen, take off makeup, repeat. But the fact of the matter is, despite your healthiest habits, aging is inevitable. That doesn't mean, however, that you're stuck having to look less than your best. The more you know about how and why your skin changes, the better equipped you are to take charge and age beautifully.

There’s a Science Behind What Makes Skin Look Youthful

It turns out, looking young isn’t subjective—there’s a real science behind youthful-looking skin and it starts with hyaluronic acid, a naturally occurring substance that gives skin its fullness. When hyaluronic acid diminishes (a natural and inevitable part of aging), that’s what causes skin to look thinner and more wrinkled.

Spotting your first frown line between your eyebrows might be the universal trigger for suddenly “feeling old,” but time isn’t the only factor that causes lines on your face. In fact, the biggest contributor to the formation of lines and wrinkles is repeated movements and muscle contraction (think: smiling, frowning, squinting)—in other words, having an expressive face, which is why lines and wrinkles may develop even in young adults.

Topical Treatments Can Only Do So Much

While a good skin care regimen should include a number of over-the-counter products, creams and lotions can only go so far. Yes, adding in moisture and plumping the skin can temporarily fade the appearance of lines and wrinkles, but they can't deliver any long-lasting results.

But there's no need to look old--you can stand up to the line with Dysport, a prescription injectable treatment for the temporary improvement in the look of moderate to severe frown lines between the eyebrows (glabellar lines) in adults less than 65 years of age.

You Can Treat Your Frown Lines And Still Look Natural

With Dysport, you can take control of your look. Aging might be inevitable, but living with frown lines between the eyebrows is not. The injectable lets you forget about your frown lines between the brows for up to 4 months*, but without having to worry about a frozen look. In other words, Dysport may be an option for women who are interested in showing off their natural beauty, who want to keep expressing themselves and continue looking like who they are.

* GL-1 and GL-3 evaluated subjects for at least 150 days following treatment. Based on investigator assessment at 120 days, the percentage of responders in GL-1 was 23% with Dysport (24/105) and 4% with placebo (2/53); in GL-3, the percentage was 29% with Dysport (58/200) and 1% with placebo (1/100).

Natural Looking Results

With 97% of users saying they would get it again*, you can trust Dysport to deliver natural looking results. The reason? Because Dysport treats your frown lines between the eyebrows without changing the look of your whole face.
*Dysport Challenge. Fort Worth, TX: Galderma Laboratories, L.P. October 2010.

The most common side effects are nose and throat irritation, headache, injection site pain, injection site skin reaction, upper respiratory tract infection, eyelid swelling, eyelid drooping, sinus inflammation, and nausea.

Dysport is Chosen By Women Everywhere

If you're under the age of 65, and don't want to worry about frown lines between the eyebrows, Dysport could be a good option for you. In just one 10 to 20 minute treatment, Dysport can help improve the look of your frown lines between the eyebrows for up to 4 months* with the majority of patients seeing results in just 2 to 3 days**. That means, less time worrying about your skin care and more time loving the skin you're in.

*GL-1 and GL-3 evaluated subjects for at least 150 days following treatment. Based on investigator assessment at 120 days, the percentage of responders in GL-1 was 23% with Dysport (24/105) and 4% with placebo (2/53); in GL-3, the percentage was 29% with Dysport (58/200) and 1% with placebo (1/100). **A secondary endpoint based on Kaplan-Meier estimates of cumulative rate of time to onset of response. The median time to onset of response was 3 days in GL-1 (Dysport 55/105 [52%], Placebo 3/53 [6%] and GL-2 (Dysport 36/71 [51%], Placebo 9/71 [13%]), and 2 days in GL-3 (Dysport 110/200 [55%], Placebo 4/100 [4%]).4-6
MP-DYS-00108 6/16

IMPORTANT SAFETY INFORMATION

Dysport is a prescription injection for temporary improvement in the look of moderate to severe frown lines between the eyebrows (glabellar lines) in adults less than 65 years of age.

Important Safety Information

What is the most important information you should know about Dysport?

Spread of Toxin Effects: In some cases, the effects of Dysport and all botulinum toxin products may affect areas of the body away from the injection site. Symptoms can happen hours to weeks after injection and may include swallowing and breathing problems, loss of strength and muscle weakness all over the body, double vision, blurred vision and drooping eyelids, hoarseness or change or loss of voice, trouble saying words clearly, or loss of bladder control. Swallowing and breathing problems can be life threatening and there have been reports of death. You are at the highest risk if these problems are pre-existing before injection.

These effects could make it unsafe for you to drive a car, operate machinery, or do other dangerous activities.

Do not have Dysport treatment if you: are allergic to Dysport or any of its ingredients (see the end of the Medication Guide for a list of ingredients), are allergic to cow’s milk protein, had an allergic reaction to any other botulinum toxin product, such as Myobloc®, Botox®, or Xeomin®, have a skin infection at the planned injection site, under 18 years of age, or are pregnant or breastfeeding.

The dose of Dysport is not the same as the dose of any other botulinum toxin product and cannot be compared to the dose of any other product you may have used.

Tell your doctor about any swallowing or breathing difficulties and all your muscle or nerve conditions such as amyotrophic lateral sclerosis [ALS or Lou Gehrig’s disease], myasthenia gravis, or Lambert-Eaton syndrome, which may increase the risk of serious side effects including difficulty swallowing and difficulty breathing.

Tell your doctor about all of your medical conditions, including if you have surgical changes to your face, very weak muscles in the treatment area, any abnormal facial change, injection site inflammation, droopy eyelids or sagging eyelid folds, deep facial scars, thick oily skin, wrinkles that can’t be smoothed by spreading them apart, or if you are pregnant or breastfeeding or planning to become pregnant or breastfeed.

Tell your doctor about all the medicines you take, including prescription and nonprescription medicines, vitamins and herbal and other natural products. Using Dysport with certain other medicines may cause serious side effects. Do not start any new medicines while taking Dysport without talking to your doctor first.

Especially tell your doctor if you: have received any other botulinum toxin product, such as Myobloc® (rimabotulinumtoxinB), Botox® (onabotulinumtoxinA), or Xeomin® (incobotulinumtoxinA), in the last four months or any in the past (be sure your doctor knows exactly which product you received, have recently received an antibiotic by injection, take muscle relaxants, take an allergy or cold medicine, or take a sleep medicine.

Common Side Effects

The most common side effects are nose and throat irritation, headache, injection site pain, injection site skin reaction, upper respiratory tract infection, eyelid swelling, eyelid drooping, sinus inflammation, and nausea.

Ask your doctor if Dysport is right for you.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Please see Dysport Full Prescribing Information including Medication Guide.

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